ADORA2A, Alomone Labs, AAR-002

We found two peer-reviewed literature reports specifically describing the validation of AAR-002 from Alomone Labs. In Ingwersen et al., Journal of Neuroinflammation, 2016, the authors observe the induction of A2a in spinal cord tissue in an active EAE model (in C57BL/6 mice) by Western blotting (Figure 1). They assess the specificity of A2aR antibody by use of a blocking peptide (Figure S1). Dilution is not reported. In Gomez-Castro et al., Science, 2021, the authors validate the specificity of the AAR-002 Alomone Labs antibody by knock down in N2a cells (Figure 20S). We have rated the antibody based on the available information and according to the pAbmAbs review criteria. We highly encourage other scientists to share their experience.