AHSA1, EnkiLife, AMRe06690

Cochaperone that stimulates HSP90 ATPase activity (By similarity). May affect a step in the endoplasmic reticulum to Golgi trafficking. Acts as a co-chaperone of HSP90AA1 (PubMed: 29127155). Activates the ATPase activity of HSP90AA1 leading to increase in its chaperone activity (PubMed: 29127155). Competes with the inhibitory co- chaperone FNIP1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins (PubMed: 27353360). Competes with the inhibitory co-chaperone TSC1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins (PubMed: 29127155).