Hopx, EnkiLife, AMRe02111
Information about this antibody
Target
Vendor
Catalog No
AMRe02111
Application
Clonality
Recombinant
Origin
Rabbit
Reactivity
Human
Conjugation
N/A
Product Link
Product Name
HOPX Rabbit Monoclonal antibody
Isotype
IgG
Accession
Q8R1H0
Concentration
1.25mg/ml. The concentration of this product may be batch-dependent.
Form
Liquid
Vendor notes
Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy (PubMed: 12297045, PubMed: 12297046). Acts as a co-chaperone for HSPA1A and HSPA1B chaperone proteins and assists in chaperone-mediated protein refolding .