Phospho-TrkA/B (Tyr490/Tyr516), EnkiLife, AMRe84924
Information about this antibody
Alt. Targets
Vendor
Catalog No
AMRe84924
Application
Clonality
Recombinant
Origin
Rabbit
Reactivity
Human, Mouse, Rat
Conjugation
N/A
Product Link
Product Name
Phospho-TrkA/B (Tyr490/Tyr516) Rabbit Monoclonal Antibody
Isotype
IgG
Accession
Q16620
Concentration
0.5mg/ml. The concentration of this product may be batch-dependent.
Form
Liquid
Vendor notes
The family of Trk receptor tyrosine kinases consists of TrkA, TrkB and TrkC. While the sequence of these family members is highly conserved, they are activated by different neurotrophins: TrkA by NGF, TrkB by BDNF or NT4, and TrkC by NT3. TrkA regulates proliferation and is important for development and maturation of the nervous system. Point mutations, deletions and chromosomal rearrangements (chimeras) cause ligand-independent receptor dimerization and activation of TrkA.