ERBB3, EnkiLife, AMRe05900
Information about this antibody
Target
Alt. Targets
Vendor
Catalog No
AMRe05900
Application
Clonality
Recombinant
Origin
Rabbit
Reactivity
Human
Conjugation
N/A
Product Link
Product Name
Phospho-ErbB3 (Y1222) (11E17) Rabbit Monoclonal Antibody
Isotype
IgG
Accession
P21860
Concentration
0.5mg/ml. The concentration of this product may be batch-dependent.
Form
Liquid
Vendor notes
Binds and is activated by neuregulins and NTAK. Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase (PubMed: 20682778). May also be activated by CSPG5 (PubMed: 15358134). Involved in the regulation of myeloid cell differentiation (PubMed: 27416908).