PKN1, EnkiLife, AMRe02452
Information about this antibody
Target
Vendor
Catalog No
AMRe02452
Application
Clonality
Recombinant
Origin
Rabbit
Reactivity
Rat
Conjugation
N/A
Product Link
Product Name
PKN1 Rabbit Monoclonal Antibody
Isotype
IgG
Accession
Q16512
Concentration
0.5mg/ml. The concentration of this product may be batch-dependent.
Form
Liquid
Vendor notes
The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.