ITGB3, EnkiLife, AMRe02164
Information about this antibody
Target
Alt. Targets
Vendor
Catalog No
AMRe02164
Application
Clonality
Recombinant
Origin
Rabbit
Reactivity
Human, Mouse
Conjugation
N/A
Product Link
Product Name
Integrin beta 3 Rabbit Monoclonal antibody
Isotype
IgG
Accession
P05106
Concentration
0.18mg/ml. The concentration of this product may be batch-dependent.
Form
Liquid
Vendor notes
Integrin alpha-IIb/beta-3 recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial surface. Fibrinogen binding enhances SELP expression in activated platelets (By similarity).