Phospho-4E BP1 (Thr46), EnkiLife, AMRe84841
Information about this antibody
Target
Alt. Targets
Vendor
Catalog No
AMRe84841
Application
Clonality
Recombinant
Origin
Rabbit
Reactivity
Human, Mouse, Rat
Conjugation
N/A
Product Link
Product Name
Phospho-4E BP1 (Thr46) Rabbit Monoclonal Antibody
Isotype
IgG
Accession
Q13541
Concentration
0.5mg/ml. The concentration of this product may be batch-dependent.
Form
Liquid
Vendor notes
Translation repressor protein 4E-BP1 (also known as PHAS-1) inhibits cap-dependent translation by binding to the translation initiation factor eIF4E. Hyperphosphorylation of 4E-BP1 disrupts this interaction and results in activation of cap-dependent translation. Both the PI3 kinase/Akt pathway and FRAP/mTOR kinase regulate 4E-BP1 activity.