PRKCB, EnkiLife, AMRe02446
Information about this antibody
Target
Alt. Targets
Vendor
Catalog No
AMRe02446
Application
Clonality
Recombinant
Origin
Rabbit
Reactivity
Human, Rat
Conjugation
N/A
Product Link
Product Name
PKC beta 2 Rabbit Monoclonal Antibody
Isotype
IgG
Accession
P05771
Concentration
0.54mg/ml. The concentration of this product may be batch-dependent.
Form
Liquid
Vendor notes
Calcium-activated, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase involved in various cellular processes such as regulation of the B-cell receptor (BCR) signalosome, oxidative stress-induced apoptosis, androgen receptor-dependent transcription regulation, insulin signaling and endothelial cells proliferation. Plays a key role in B-cell activation by regulating BCR-induced NF-kappa-B activation. Mediates the activation of the canonical NF-kappa-B pathway (NFKB1) by direct phosphorylation of CARD11/CARMA1 at 'Ser-559', 'Ser-644' and 'Ser-652'.