BUB1B, EnkiLife, AMRe02919
Information about this antibody
Target
Alt. Targets
Vendor
Catalog No
AMRe02919
Application
Clonality
Recombinant
Origin
Rabbit
Reactivity
Human, Hamster
Conjugation
N/A
Product Link
Product Name
BUBR1 Rabbit Monoclonal Antibody
Isotype
IgG
Accession
O60566
Concentration
0.63mg/ml. The concentration of this product may be batch-dependent.
Form
Liquid
Vendor notes
Essential component of the mitotic checkpoint. Required for normal mitosis progression. The mitotic checkpoint delays anaphase until all chromosomes are properly attached to the mitotic spindle. One of its checkpoint functions is to inhibit the activity of the anaphase-promoting complex/cyclosome (APC/C) by blocking the binding of CDC20 to APC/C, independently of its kinase activity. The other is to monitor kinetochore activities that depend on the kinetochore motor CENPE. Required for kinetochore localization of CENPE.