BAK1, EnkiLife, AMRe01714
Information about this antibody
Target
Alt. Targets
Vendor
Catalog No
AMRe01714
Application
Clonality
Recombinant
Origin
Rabbit
Reactivity
Human
Conjugation
N/A
Product Link
Product Name
Bak Rabbit Monoclonal antibody
Isotype
IgG
Accession
Q16611
Concentration
0.18mg/ml. The concentration of this product may be batch-dependent.
Form
Liquid
Vendor notes
Bak is a proapoptotic member of the Bcl-2 family. This protein is located on the outer membrane of mitochondria and is an essential component for transduction of apoptotic signals through the mitochondrial pathway. Upon apoptotic stimulation, an upstream stimulator like truncated BID (tBID) induces conformational changes in Bak to form oligomer channels in the mitochondrial membrane for cytochrome c release. The release of cytochrome c to the cytosol activates the caspase-9 pathway and eventually leads to cell death.