APC, EnkiLife, AMRe02900
Information about this antibody
Target
Vendor
Catalog No
AMRe02900
Application
Clonality
Recombinant
Origin
Rabbit
Reactivity
Human
Conjugation
N/A
Product Link
Product Name
APC Rabbit Monoclonal antibody
Isotype
IgG
Accession
P25054
Concentration
0.18mg/ml. The concentration of this product may be batch-dependent.
Form
Liquid
Vendor notes
Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF)-induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex.