EIF2S1, EnkiLife, AMRe21372
Information about this antibody
Target
Alt. Targets
Vendor
Catalog No
AMRe21372
Application
Clonality
Recombinant
Origin
Rabbit
Reactivity
Human, Mouse, Rat, Fish
Conjugation
N/A
Product Link
Product Name
eIF2α Rabbit Monoclonal Antibody
Isotype
IgG,Kappa
Accession
P05198
Concentration
0.3mg/ml. The concentration of this product may be batch-dependent.
Form
Liquid
Vendor notes
Cell localization: Cytoplasm. The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al. , 1987 [PubMed 2948954]). [supplied by OMIM, Feb 2010],