BCL2L1, EnkiLife, AMRe07516
Information about this antibody
Target
Alt. Targets
Vendor
Catalog No
AMRe07516
Application
Clonality
Recombinant
Origin
Rabbit
Reactivity
Human, Mouse, Rat
Conjugation
N/A
Product Link
Product Name
Bcl-XL (4B16) Rabbit Monoclonal Antibody
Isotype
IgG
Accession
Q07817
Concentration
0.48mg/ml. The concentration of this product may be batch-dependent.
Form
Liquid
Vendor notes
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage- dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis. Isoform Bcl-X(S) promotes apoptosis.