TP73, EnkiLife, AMRe15668
Information about this antibody
Target
Alt. Targets
Vendor
Catalog No
AMRe15668
Application
Clonality
Recombinant
Origin
Rabbit
Reactivity
Human, Mouse
Conjugation
N/A
Product Link
Product Name
p73 (8W9) Rabbit Monoclonal Antibody
Isotype
IgG
Accession
O15350
Concentration
0.5mg/ml. The concentration of this product may be batch-dependent.
Form
Liquid
Vendor notes
p73 IS a protein of the p53 family of proteins. Participates in the apoptotic response to DNA damage. Phosphorylated in a cell cycle-dependent manner and negatively regulated by CDKs. When overproduced, activates transcription from p53-responsive promoters and induces apoptosis. May be a tumor suppressor protein. Seven alternatively-spliced isoforms have been described. Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.