CEACAM5, EnkiLife, AMRe08610
Information about this antibody
Target
Alt. Targets
Vendor
Catalog No
AMRe08610
Application
Clonality
Recombinant
Origin
Rabbit
Reactivity
Human
Conjugation
N/A
Product Link
Product Name
CEA(CD66e) (7M6) Rabbit Monoclonal Antibody
Isotype
IgG
Accession
P06731
Concentration
0.48mg/ml. The concentration of this product may be batch-dependent.
Form
Liquid
Vendor notes
Carcinoembryonic antigen (CEA), also known as CD66e or CEACAM5, is a 180-200 kDa cell surface glycoprotein whose expression is elevated in intestinal carcinomas and other tumors. CEA mediates cell adhesion, though little more is known about its biological activity. Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression (PubMed: 2803308, PubMed: 10910050, PubMed: 10864933). Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6 (PubMed: 2803308). Plays a role as an oncogene by promoting tumor progression; induces resistance to anoikis of colorectal carcinoma cells (PubMed: 10910050).