GLS, EnkiLife, AMRe11506
Information about this antibody
Target
Alt. Targets
Vendor
Catalog No
AMRe11506
Application
Clonality
Recombinant
Origin
Rabbit
Reactivity
Human
Conjugation
N/A
Product Link
Product Name
Glutaminase (3F15) Rabbit Monoclonal Antibody
Isotype
IgG
Accession
O94925
Concentration
0.36mg/ml. The concentration of this product may be batch-dependent.
Form
Liquid
Vendor notes
Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate in the brain. Isoform 2 lacks catalytic activity. Isoform 1 and isoform 3 are activated by phosphate. Inhibited by BPTES. BPTES binds between subunits and favors dissociation of the tetramer into dimers. Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate, the main excitatory neurotransmitter in the brain (PubMed: 30575854, PubMed: 30239721, PubMed: 30970188).