RPA2, EnkiLife, AMRe21449
Information about this antibody
Target
Alt. Targets
Vendor
Catalog No
AMRe21449
Application
Clonality
Recombinant
Origin
Rabbit
Reactivity
Human, Mouse, Rat
Conjugation
N/A
Product Link
Product Name
RPA32/RPA2 Rabbit Monoclonal Antibody
Isotype
IgG,Kappa
Accession
P15927
Concentration
0.3mg/ml. The concentration of this product may be batch-dependent.
Form
Liquid
Vendor notes
Cell localization: Nucleus. function: Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions. , PTM: Phosphorylated in a cell-cycle-dependent manner (from the S phase until mitosis). Phosphorylated by ATR upon DNA damage, which promotes its translocation to nuclear foci. Can be phosphorylated in vitro by PRKDC/DNA-PK in the presence of Ku and DNA, and by CDC2. , subcellular location: Also present in PML nuclear bodies. Redistributes to discrete nuclear foci upon DNA damage. , subunit: Heterotrimer of 70, 32 and 14 kDa chains. The DNA-binding activity may reside exclusively on the 70 kDa subunit. Binds to SERTAD3/RBT1. Interacts with TIPIN. ,