NOTCH1, EnkiLife, AMRe02351
Information about this antibody
Target
Alt. Targets
Vendor
Catalog No
AMRe02351
Application
Clonality
Recombinant
Origin
Rabbit
Reactivity
Human, Mouse, Rat
Conjugation
N/A
Product Link
Product Name
Notch1 Rabbit Monoclonal Antibody
Isotype
IgG
Accession
P46531
Concentration
0.3mg/ml. The concentration of this product may be batch-dependent.
Form
Liquid
Vendor notes
Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting.