EPCAM, EnkiLife, AMRe10506
Information about this antibody
Target
Alt. Targets
Vendor
Catalog No
AMRe10506
Application
Clonality
Recombinant
Origin
Rabbit
Reactivity
Human
Conjugation
N/A
Product Link
Product Name
EpCAM (15A7) Rabbit Monoclonal Antibody
Isotype
IgG
Accession
P16422
Concentration
0.28mg/ml. The concentration of this product may be batch-dependent.
Form
Liquid
Vendor notes
Epithelial cell adhesion and activating molecule (EpCAM/CD326) is a transmembrane glycoprotein that mediates Ca2+ independent, homophilic adhesions on the basolateral surface of most epithelial cells. The antigen is being used as a target for immunotherapy treatment of human carcinomas. May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.