XRCC6, EnkiLife, AMRe03061
Information about this antibody
Target
Alt. Targets
Vendor
Catalog No
AMRe03061
Application
Clonality
Recombinant
Origin
Rabbit
Reactivity
Human
Conjugation
N/A
Product Link
Product Name
Ku70 Rabbit Monoclonal Antibody
Isotype
IgG
Accession
P12956
Concentration
0.53mg/ml. The concentration of this product may be batch-dependent.
Form
Liquid
Vendor notes
It works in the 3'-5' direction. Binding to DNA may be mediated by XRCC6. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The XRCC5/6 dimer acts as regulatory subunit of the DNA-dependent protein kinase complex DNA-PK by increasing the affinity of the catalytic subunit PRKDC to DNA by 100-fold. The XRCC5/6 dimer is probably involved in stabilizing broken DNA ends and bringing them together.