RAB4A, EnkiLife, AMRe16789
Information about this antibody
Target
Alt. Targets
Vendor
Catalog No
AMRe16789
Application
Clonality
Recombinant
Origin
Rabbit
Reactivity
Human, Mouse, Rat
Conjugation
N/A
Product Link
Product Name
Rab4 (18S8) Rabbit Monoclonal Antibody
Isotype
IgG
Accession
P20338
Concentration
0.5mg/ml. The concentration of this product may be batch-dependent.
Form
Liquid
Vendor notes
The protein encoded by this gene belongs to the rab family. Rab4A protein is involved in the regulation of procathepsin L secretion, it was either inhibited by expression of a Rab4A dominant-negative mutant or increased by overexpression of the wild-type Rab4A in human melanoma cells. Small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state (PubMed: 15907487, PubMed: 16034420). Involved in protein transport (PubMed: 29425100). Plays a role in vesicular traffic. Mediates VEGFR2 endosomal trafficking to enhance VEGFR2 signaling (PubMed: 29425100). Acts as a regulator of platelet alpha- granule release during activation and aggregation of platelets (By similarity).