Tuberin, EnkiLife, AMRe83799
Information about this antibody
Target
Vendor
Catalog No
AMRe83799
Application
Clonality
Recombinant
Origin
Rabbit
Reactivity
Human, Mouse, Rat
Conjugation
N/A
Product Link
Product Name
Tuberin Rabbit Monoclonal Antibody
Isotype
IgG
Accession
P49815
Concentration
0.49mg/ml. The concentration of this product may be batch-dependent.
Form
Liquid
Vendor notes
Catalytic component of the TSC-TBC complex, a multiprotein complex that acts as a negative regulator of the canonical mTORC1 complex, an evolutionarily conserved central nutrient sensor that stimulates anabolic reactions and macromolecule biosynthesis to promote cellular biomass generation and growth. Within the TSC-TBC complex, TSC2 acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity of mTORC1.