PERK, EnkiLife, AMRe21506
Information about this antibody
Target
Alt. Targets
Vendor
Catalog No
AMRe21506
Application
Clonality
Recombinant
Origin
Rabbit
Reactivity
Human, Mouse, Rat
Conjugation
N/A
Product Link
Product Name
PERK Rabbit Monoclonal Antibody
Isotype
IgG,Kappa
Accession
Q9NZJ5
Concentration
0.3mg/ml. The concentration of this product may be batch-dependent.
Form
Liquid
Vendor notes
Cell localization: Endoplasmic reticulum membrane. The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. [provided by RefSeq, Sep 2015],