DNAJB6, EnkiLife, AMRe01918
Information about this antibody
Target
Vendor
Catalog No
AMRe01918
Application
Clonality
Recombinant
Origin
Rabbit
Reactivity
Human, Mouse, Rat
Conjugation
N/A
Product Link
Product Name
DNAJB6 Rabbit Monoclonal Antibody
Isotype
IgG
Accession
O75190
Concentration
0.64mg/ml. The concentration of this product may be batch-dependent.
Form
Liquid
Vendor notes
Plays an indispensable role in the organization of KRT8/KRT18 filaments. Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin. Suppresses aggregation and toxicity of polyglutamine-containing, aggregation-prone proteins. Isoform B but not isoform A inhibits huntingtin aggregation. Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70. Also reduces cellular toxicity and caspase-3 activity.