ARNT, EnkiLife, AMRe03025
Information about this antibody
Target
Alt. Targets
Vendor
Catalog No
AMRe03025
Application
Clonality
Recombinant
Origin
Rabbit
Reactivity
Human, Mouse, Rat, Hamster
Conjugation
N/A
Product Link
Product Name
HIF1 beta Rabbit Monoclonal Antibody
Isotype
IgG
Accession
P27540
Concentration
0.53mg/ml. The concentration of this product may be batch-dependent.
Form
Liquid
Vendor notes
HIF-1β is also known as AhR nuclear translocator (ARNT) due to its ability to partner with the aryl hydrocarbon receptor (AhR) to form a heterodimeric transcription factor complex. Together with AhR, HIF-1β plays an important role in xenobiotics metabolism. In addition, a chromosomal translocation leading to a TEL-ARNT fusion protein is associated with acute myeloblastic leukemia. Studies also found that ARNT/HIF-1β expression levels decrease significantly in pancreatic islets from patients with type 2 diabetes, suggesting that HIF-1β plays an important role in pancreatic β-cell function.