ACTA2, EnkiLife, AMRe03761
Information about this antibody
Target
Alt. Targets
Vendor
Catalog No
AMRe03761
Application
Clonality
Recombinant
Origin
Rabbit
Reactivity
Human, Mouse, Rat
Conjugation
N/A
Product Link
Product Name
alpha Smooth Muscle Actin Rabbit Monoclonal Antibody
Isotype
IgG
Accession
P62736
Concentration
0.63mg/ml. The concentration of this product may be batch-dependent.
Form
Liquid
Vendor notes
Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Defects in ACTA2 are the cause of aortic aneurysm familial thoracic type 6 (AAT6) [MIM: 611788]. They are primarily associated with a characteristic histologic appearance known as 'medial necrosis' or 'Erdheim cystic medial necrosis' in which there is degeneration and fragmentation of elastic fibers, loss of smooth muscle cells, and an accumulation of basophilic ground substance.