CYBB, EnkiLife, AMRe21610
Information about this antibody
Target
Alt. Targets
Vendor
Catalog No
AMRe21610
Application
Clonality
Recombinant
Origin
Rabbit
Reactivity
Human, Mouse, Rat
Conjugation
N/A
Product Link
Product Name
NOX2 Rabbit Monoclonal Antibody
Isotype
IgG,Kappa
Accession
P04839
Concentration
0.3mg/ml. The concentration of this product may be batch-dependent.
Form
Liquid
Vendor notes
Cell localization: Membranous. Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole. [provided by RefSeq, Jul 2008],