MYC, EnkiLife, KVAb01452
Information about this antibody
Target
Alt. Targets
Vendor
Catalog No
KVAb01452
Application
Clonality
mAb
Origin
Mouse
Reactivity
Human
Conjugation
N/A
Product Link
Product Name
KD-Validated MYC Mouse Monoclonal Antibody
Isotype
Mouse IgG1 kappa
KO/KD-Validated
Yes
Accession
P01106
Purity
Affinity purification
Form
Liquid
Vendor notes
This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017]