PDK1, EnkiLife, KVAb00941
Information about this antibody
Target
Alt. Targets
Vendor
Catalog No
KVAb00941
Application
Clonality
Recombinant
Origin
Rabbit
Reactivity
Human, Mouse, Rat
Conjugation
N/A
Product Link
Product Name
KD-Validated Pyruvate Dehydrogenase Kinase 1 Recombinant Rabbit Monoclonal Antibody
Isotype
Rabbit IgG
KO/KD-Validated
Yes
Accession
Q15118
Purity
Affinity purification
Form
Liquid
Vendor notes
Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2013]