TFE3, EnkiLife, KVAb00180
Information about this antibody
Target
Alt. Targets
Vendor
Catalog No
KVAb00180
Application
Clonality
Recombinant
Origin
Rabbit
Reactivity
Human, Mouse, Rat
Conjugation
N/A
Product Link
Product Name
KD-Validated TFE3 Recombinant Rabbit Monoclonal Antibody
Isotype
Rabbit IgG
KO/KD-Validated
Yes
Accession
P19532
Purity
Affinity purification
Form
Liquid
Vendor notes
This gene encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes. The encoded protein promotes the expression of genes downstream of transforming growth factor beta (TGF-beta) signaling. This gene may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins. Translocation partners include PRCC (papillary renal cell carcinoma), NONO (non-POU domain containing, octamer-binding), and ASPSCR1 (alveolar soft part sarcoma chromosome region, candidate 1), among other genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]