EIF2AK2, EnkiLife, KVAb00674
Information about this antibody
Target
Alt. Targets
Vendor
Catalog No
KVAb00674
Application
Clonality
mAb
Origin
Mouse
Reactivity
Human
Conjugation
N/A
Product Link
Product Name
KD-Validated eIF-2A Protein Kinase 2 Mouse Monoclonal Antibody
Isotype
Mouse IgG1
KO/KD-Validated
Yes
Accession
P19525
Purity
Affinity purification
Form
Liquid
Vendor notes
The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. The encoded protein plays an important role in the innate immune response against multiple DNA and RNA viruses. [provided by RefSeq, Jul 2021]