TSC2, EnkiLife, KVAb00178
Information about this antibody
Target
Alt. Targets
Vendor
Catalog No
KVAb00178
Application
Clonality
Recombinant
Origin
Rabbit
Reactivity
Human, Mouse, Rat
Conjugation
N/A
Product Link
Product Name
KD-Validated Tuberin Recombinant Rabbit Monoclonal Antibody
Isotype
Rabbit IgG
KO/KD-Validated
Yes
Accession
P49815
Purity
Affinity purification
Form
Liquid
Vendor notes
This gene is a tumor suppressor gene that encodes the growth inhibitory protein tuberin. Tuberin interacts with hamartin to form the TSC protein complex which functions in the control of cell growth. This TSC protein complex negatively regulates mammalian target of rapamycin complex 1 (mTORC1) signaling which is a major regulator of anabolic cell growth. Mutations in this gene have been associated with tuberous sclerosis and lymphangioleiomyomatosis. [provided by RefSeq, May 2022]