CASP3, EnkiLife, KVAb00182
Information about this antibody
Target
Alt. Targets
Vendor
Catalog No
KVAb00182
Application
Clonality
Recombinant
Origin
Rabbit
Reactivity
Human
Conjugation
N/A
Product Link
Product Name
KD-Validated Caspase 3 Recombinant Rabbit Monoclonal Antibody
Isotype
Rabbit IgG
KO/KD-Validated
Yes
Accession
P42574
Purity
Affinity purification
Form
Liquid
Vendor notes
The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. [provided by RefSeq, Aug 2017]