DNMT1, EnkiLife, KVAb00803
Information about this antibody
Target
Alt. Targets
Vendor
Catalog No
KVAb00803
Application
Clonality
Recombinant
Origin
Rabbit
Reactivity
Human, Mouse, Rat
Conjugation
N/A
Product Link
Product Name
KD-Validated DNA Methyltransferase 1 Recombinant Rabbit Monoclonal Antibody
Isotype
Rabbit IgG
KO/KD-Validated
Yes
Accession
P26358
Purity
Affinity purification
Form
Liquid
Vendor notes
This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]