CXCR2, rat mAb clone 242216, R&D Systems, MAB2164-100

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One User Review

  • Works well in neutralization of neutrophil migration against ELR+ CXC chemokines in vitro, but questionable neutralization effect in vivo because the mAb also immunodepletes circulating neutrophils.

    2.5 or 3.75 mg/kg i.p. for neutralization.

    For more information see Aquino et al. PLOS 2020, “Host syndecan-1 promotes listeriosis by inhibiting intravascular neutrophil extracellular traps”.
    https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1008497#sec011

    Western blotNot Rated
    ImmunostainingNot Rated
    IPNot Rated
    ChIPNot Rated
    ELISANot Rated
    Flow cytometry55555
    LuminexNot Rated
    EMNot Rated

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Western blot
Immunostaining
IP
ChIP
ELISA
Flow cytometry
Luminex
EM