Related topics: Alphabetical list, Chemotaxis, G-protein coupled receptor, Receptor, Transducer
On June 23, 2020
Pyong Woo Park wrote:
Works well in neutralization of neutrophil migration against ELR+ CXC chemokines in vitro, but questionable neutralization effect in vivo because the mAb also immunodepletes circulating neutrophils.
2.5 or 3.75 mg/kg i.p. for neutralization.
For more information see Aquino et al. PLOS 2020, “Host syndecan-1 promotes listeriosis by inhibiting intravascular neutrophil extracellular traps”.